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Clinical and translational research includes laboratory-based
research and research in human subjects, populations and communities.
“T1” (bench to bedside/laboratory to human) translational research
includes laboratory-based research aimed at clarifying mechanisms of
disease, developing measures or markers of disease presence, severity
or improvement, and developing drugs or devices to treat disease or im
prove health. Clinical research includes studies in human subjects
including surveys, cross-sectional studies, case series,
case-control studies, cohort studies, first-in-human,
proof of principle, and all phases of clinical trials. “T2” (bedside
to the community/evidence to practice) translational research includes
studies of T2 research identifies community, patient, physician and
organizational factors that serve as barriers and facilitators to
translation; develops novel intervention and implementation strategies
to increase translation, such as quality improvement programs or
policies; and evaluates the impact of strategies to increase translation
of relevant healthy behaviors and processes of care.
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